n-3多不饱和脂肪酸对动物炎症·免疫和细胞因子的调节作用
Regulation of(n-3) Polyunsaturated Fatty Acid to Inflammation and Cytokine Production
摘要
综述了n-3多不饱和脂肪酸对动物炎症、感染和细胞因子的作用效果。
The production of pro-inflammatory cytokine,such as interleukin-1 and tumor necrosis factor,is critical in the response to infection. However, overproduction of the cytokines might be harmful. It was suggested that n-3 fatty acid suppressed inflammation and improved the course of infection through the decreasing of the production of pro-inflammatory cytokines.
出处
《安徽农业科学》
CAS
北大核心
2006年第14期3367-3370,共4页
Journal of Anhui Agricultural Sciences
参考文献36
-
1MEER V M. Options for the treatment of serious infections with interleukin-1 [J].Biotherapy, 1989( 1 ) : 313 -317.
-
2COMINELLI F,NAST C C,CLARK B D,et al. Interleukin I(IL-1)gene expression,synthesis,and effect of specific IL-1 receptor blickade in rabbit immune complex colitis [J]. J Clin Invest,1990( 86 ) : 972-980.
-
3OHLSSON K,BJORK P,BERGENFELDT M,et al. Interleukin-1 receptor antagonist reduces mortality from endotoxin shock [J].Nature, 1990,348 : 550-552.
-
4TRACEY K J,FONG Y,HESSE D G,et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia[J]. Nature, 1987(330):662-664.
-
5KELLY V E,FERRETYO A,IZUI S,et al, A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites,and suppresses lupus in MRL-I pr mice[J].J Immunol, 1985( 134): 1 914-1 919,
-
6PRICKETY J D,ROBINSON D R,STEINBERG A D. Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic prevents proteinuria and prolongs survival in (NZB xNZW)F1 mice[J]. J Clin Invest, 1981 ( 68 ) :556-559.
-
7LESLIE C A,GONNERMAN W A,ULLMAN M D,et al. Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibilily in mice[J]. J Exp Med,1985( 162): 1 336-1 349.
-
8CATHCART E S,MORTENSEN R F,LESLIE C A,et al. A fish oil diet inhibits amyloid P component (AP)acute phase responses in arthritis susceptible mice[J]. J Immunol,1987(139):89-91.
-
9BOLCK K J,HO B,XU L L,et al. Effect of fish-fat or beef-fat supplemented diet on immune complex-inducedenteropathy in the rat[J], Prostaglandins, 1989( 38 ) : 385-396,
-
10MCCARTHY D O,KLUGER M J,VANDER A J. Suppression of food intake during infections:is interleukin-1 involved [J]. Am J Clin Nutr,1985(42):1 179-1 182.