Ca-P-Si系微晶玻璃的制备及生物活性分析

Synthesis of Ca-P-Si System Glass-ceramics and Analysis of Its Bioactivity

采用溶胶—凝胶法制备了CaO-P2O5-SiO2系微晶玻璃,利用体外模拟(in vitro)实验方法,借助SEM和EDX等分析测试手段研究了将其压片试样静态浸入模拟生理体液(SBF)前后样品表面的形貌和组成的变化。结果显示,浸泡时间不同,压片的玻璃相表面碳酸羟基磷灰石(HCA)的生成量也不同,随着浸泡时间增长,HCA含量随之增加,从而证实了其生物活性的存在。

CaO-P_2O_5-SiO_2 system glass-ceramics were prepared using sol-gel method.The change of morphology and composition on surface of the tabletted-sample before and after in vitro test(soaked in simulated body fluid at static state) were investigated by means of SEM and EDX.It was showed that the amount of HCA on the surface of glass phase in the sample is different with the change of soaking time.The increase of HCA with soaking time verifies the presence of bioactivity.