摘要
采用数值模拟的方法,研究主动脉弯曲血管中的定常/脉动流动及低密度脂肪蛋白(LDL)和血清白蛋白(Albumin)传质.计算结果表明,对于主动脉弓模型,二次流漩涡的位置随时间变化.在弯曲变化比较剧烈的区域大分子浓度较高,壁面浓度外壁高于内壁.这些流动变化比较剧烈的区域可能是动脉硬化或血栓形成的危险区域.
A numerical analysis of the steady/pulsatile flow and macromolecular (such as LDL and Albumin) transport in curved blood vessels was carried out. The computational results predict that the vortex of the secondary flow is time-dependent in the aortic arch. The concentration of macromolecule concentrates at the region of sharp curve, and the wall concentration at the outer part is higher than that at the inner part. Atherosclerosis is prone to develop in such regions with sharp flow.
出处
《应用数学和力学》
CSCD
北大核心
2006年第9期1071-1078,共8页
Applied Mathematics and Mechanics
基金
国家自然科学基金资助项目(10372007
30571900
10572006)
北京市自然科学基金资助项目(7062015)
关键词
弯曲血管
血液流动
大分子传质
动脉粥样硬化
curved blood vessels
blood flow
macromolecular transport
atherosclerosis