人类基因组信息与中医

The Informatics of Human Genome and Traditional Chinese Medicine

以基因为桥梁,以《易经》及《内经》的阴阳集论为理论基础和方法论,将古代的功能系统论与现代的结构系统论相融合,利用虚拟技术,将NCBI-OMIM的基因信息,编制成一个以网页文件形式保存的二级数据库,称人类病态基因库,有16大类:即基因本性、普通基因表型基因谱,内源基因相互作用,具庄象与器官性疾病、中医、西医诊断、环境反应、综合征、疾病、神经内分泌、肿瘤、心理行为、病态、体内信息因子、基因表达。外源基因与内源基因的相互作用等4711条词汇(文件),它的优点是:实用于人类模糊认识事物的智能特点,适合对事物本体(阴阳)的揭示,贴近临床。

Guided by the theory and methodology of yin-yang set derived from Changing Book and Medicine Canon, and using genetics as a bridge, we have tried to bring together the ancient functional systematology and modern structural one as well as Eastern and Western medicine, thereby promoting the modernization of traditional Chinese medicine （TCM） in theory and in clinical practice. Herein, we used virtual technology to transform the genetic information in OMIM of NCBI （National Center for Biotechnology Information of USA, http：//www.ncbi.nlm.nih.gov ） into a secondary database in the form of webpages. There are sixteen kinds of the database named gene morbidity ones as followings as： the nature of gene, the profile of common phenotype, a interaction of endogenous, the disease of a organ or a viscera pathogenesis phenomenon, TCM, the sign of diagnosis of western medicine, the gene response to environment, syndrome, disease, nerve and -endocrine, tumor and cancer, psychology and behavior, morbidity, endo-factor of molecular information, expression, the interaction between endogenous and exogenous in which there is 4711 words, files. The advantages of the database are its aptness for using human fuzzy intelligence to recognize things, suitability to uncovering the noumenon （yinyang） nature of an object and applicability to clinical use.