期刊文献+

妇科手术患者围术期外周血T细胞亚群的变化及其与血浆儿茶酚胺的相关性

下载PDF
导出
摘要 妇科择期手术患者20例。采用连续硬膜外麻醉,术毕前10min硬膜外注入吗啡2mg。于术前及术后第1、3天晨抽取空腹静脉血,测定外周血T细胞亚群以及血浆儿茶酚胺(CA)。结果显示,术后第1、3天外周血CD3+及CD4+细胞百分率较术前明显降低(P均<0.01),而CA较术前明显升高(P<0.01)。CD3+细胞百分率与CA水平呈负相关,r=-0.772,P<0.01;CD4+细胞百分率与CA无直线相关关系,r=-0.350,P>0.05。提示妇科手术患者围术期细胞免疫及内分泌状态发生变化,CD3+细胞的变化与CA水平变化有关。
出处 《山东医药》 CAS 北大核心 2006年第24期36-36,共1页 Shandong Medical Journal
  • 相关文献

参考文献2

二级参考文献27

  • 1Alonzo NC, Bayer BM. Opioids, immunology, and host defenses of intr&avenous drug abusers. Infect Dis Clin North Am, 2002, 16: 553-569.
  • 2Li Y, Merrill JD, Mooney K, et al. Morphine enhances HIV infection of neonatal macrophages. Pediatr Res, 2003,54: 282-288.
  • 3Yaksh TL, Rudy TA. Chronic catheterization of the spinal subarachnoid space. Physiol Behav, 1976,17:1031-1036.
  • 4Dubuisson D, Dennis SG.The formalin test: a quantitative study of the analgesic effects of morphine,meperidine, and brain stem stimulation in rats and cats. Pain, 1977,4:161-174.
  • 5Korzeniewski C, Callewaert DM.An enzyme-release assay for natural cvtotoxicitv. J Immunol Methods, 1983,64: 313-320.
  • 6李思嘉 韩济生.大鼠蛛网膜下腔注射5-羟色胺和吗啡的镇痛作用[J].生理学报,1986,38:19-25.
  • 7RahimRT, MeisslerJJJr, CowanA,etal. Administrationofmu-, kappaor delta2-receptor agonists via. osmotic minipumps suppresses murine splenic antibody responses. Int Immunopharmacol, 2001,1: 2001-2009.
  • 8Nelson CJ, Dykstra LA, Lysle DT. Comparison of the time course of morphine′ s analgesic and immunologic effects. Anesth Analg, 1997,85:620-626.
  • 9Tsai YC, Won SJ, Lin MT. Effects of morphine on immune response in rats with sciatic constriction injury. Pain, 2000,88: 155-160.
  • 10Weber RJ, Pert A. The periaqueductal gray matter mediates opiateinduced immunosuppression. Science, 1989,245: 188-190.

共引文献54

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部