摘要
目的:探讨单纯放射治疗、手术加放射治疗瘢痕疙瘩的临床疗效。方法:回顾性分析直线加速器(6MeV)电子束放射治疗104例瘢痕疙瘩,其中单纯放疗50例,手术切除后放疗54例。照射剂量14-16 Gy 44例,16-20 Gy 60例,每次2 Gy,共1.5-2周。术后放疗在24 h内开始30例,拆线后开始24例。结果:(1)单纯放疗与手术后放疗比较:治愈率分别为44%和55.6%,有效率分别为66%和83.5%,两组比较有显著差异(P<0.05)。(2)术后24 h内放疗与拆线后放疗比较:治愈率分别为83.3%和41.7%,有效率分别为96.7%和62.5%,两组比较有显著差异(P<0.05)。(3)放疗剂量为Dt =14-16 Gy和Dt=16-20 Gy的治愈率分别为45.4%和52.7%,有效率均为75%,两组比较无显著差异(P>0.05)。结论:术后放疗是治疗瘢痕疙瘩的有效方法,尤其是术后24 h内放疗效果好于拆线后放疗。
Objective:To study the efficaey of keloid with radiotherapy only and postoperative radiation therapics treatment. Methods : 104 patients with keloid patients were treated with accelerator of 6MeV-β ray, the total doses of radiation were 14-20 Gy,2 Gy one time,5 times one week 30 cases were managed by radiotherapy in while 24 h after operation,24 cases were not managed until stitches. Results: (1)The effective rate of radiotherapy was 60 %, the postoperative radiotherapy was 83.5 %, the latter was significantly higher than the former(P〈0. 05). (2)The effective rate of radiotherapy in 24 h after operation was96. 7% ,after stitches was 62.5% ,the former was significantly higher than the latter(P〈0. 05). (3)The doses of radiation between 14- 16 Gy was 75% ,the same as the doses between 16-20 Gy,there was no significant differences (P〉0. 05). Conclusions : Postoperative radiation therapy has better curative effect in keloid treatment,and it is better to be performed with 24 h after operation.
出处
《中国临床医学》
北大核心
2006年第4期690-691,共2页
Chinese Journal of Clinical Medicine