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雌激素在血栓闭塞性脉管炎中的作用探讨 被引量:3

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摘要 目的:以多发性大动脉炎模型做试验,测定血浆雌激素浓度及血流动力学改变在血栓闭塞性脉管炎中的作用。方法:选用SD雌性大鼠15只,随机分为试验组(n=8)和对照组(n=7)。观察两组血浆雌激素、孕激素及血流动力学指标的变化。结果:试验组血浆雌激素、孕激素水平明显高于对照组;试验组和对照组腹主动脉血流动力学参数有明显差异。结论:高雌激素血症引起血流动力学的一系列变化,是多发性大动脉炎血管重构的重要因素之一,在血栓闭塞性脉管炎的发病中起重要作用。
出处 《山西职工医学院学报》 CAS 2006年第3期30-32,共3页 Journal of Shanxi Medical College for Continuing Education
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