肝硬化患者血浆胃动素水平研究

Study on Plasma MTL Level in Patiens with Hepatocirrhosis

对４６例肝硬化患者进行了血浆胃动素（ＭＴＬ）水平测定，同时检查了有关肝功能指标，观察两者之间的关系。结果表明，肝硬化ＭＴＬ升高。ＭＴＬ值按Ｃｈｉｌｄ分级，Ｃ级＞Ｂ级＞Ａ级，相差均具有极显著意义；与血浆白蛋白呈明显负相关，与血浆总胆红素、血肌酐呈明显正相关，与谷丙转氨酶（ＧＰＴ）无明显相关性。

Plasma MTL was determined in 46 patients with hepatocirrhosis decompensation and related liver function test was performed.The relationship between them was compared.The results showed that plasma MTL in patients with hepatocirrhosis was higher than that in normal,and MTL level in C grade>B grade>A grade,according to child grading correlation is different significantly.MTL level has a negative correlation with plasma albumin,it has a positive corelation with total plasma bilirubin and blood creatinine,MTL level has no obvious correlation with GPT.It has a certain clinical significance to judge liver function,and reflects not only the pathophysiological process of hepatocirrhosis but also liver function.The mechanism of MTL elevation is because of reduction of the inactivation function of the liver,portal hypertension,decrease of the excretory function of the kidney.