摘要
目的：探讨乳腺癌新辅助化疗的可行性和不良反应。方法：从2004年4月～2005年6月。对93例Ⅱ期～Ⅲ期可手术乳腺癌病例，随机分为两组：术前化疗组（试验组），行术前化疗2～3个周期，化疗结束后7～10天再予手术，共48例；45例为同期直接手术的乳腺癌病例（对照组）。结果：试验组化疗总有效率为72.9％（35／48）；两组的手术难度、手术时间、术中出血量及术后引流量均无显著性差异（P〉0．05）。结论：对可手术乳腺癌患者行术前新辅助化疗可使原发病灶缩小，缩小手术范围，提高患者术后的生活质量；未增加手术并发症，可望提高疗效。
Objective：To explore the efficacy and its side effects of neo - adjuvant chemotherapy on breast cancer patients. Methods ： From Apr. 2004 to Jun. 2005, 93 cases of breast cancer which were perforformed surgical treatment were divided randomly into two groups 48 with neo - adjuvant chemotherapy （ treatment group） for about 2 to 3 cycles and the operaton was performed 7 - 10 days later other 45 with operation without preoperation treatment（ control group）. Results： The over all effective rate of the treatmen tgroup was 72.9% （35/48）. There was no significant difference on the difficutly of operation, the operation time, the blood loss during operation and the postoperative drainage volume between the two groups. Conclusion： Neo - adjuvant chemotherapy can decrease the size of primary tumor ,reduce the complexity of surgey and improve the quality of life of breast canaer patients. Neo - adjuvant chemotherapy is effective in the treatment of brest cancaer.
出处
《现代肿瘤医学》
CAS
2006年第9期1071-1073,共3页
Journal of Modern Oncology
关键词
乳腺癌
新辅助化疗
手术
breast cancer
neo- adjuvant chemotherapy
operation
