Clinical profile of gastric cancer in Khuzestan, southwest of Iran

瞄准：分析特征流行病学，临床并且在有胃的癌的病人之中的幸存模式。方法：我们回顾地从 1996 年 9 月 1 日在阿瓦十 Jundishapur 大学医院(AJSUH ) 学习了 186 个胃的腺癌病人的特征到 2002 年 9 月 1 日。所有病人有证实 histopathologically 的恶意。人口统计的变量，胃的癌症(GC ) 的家庭历史，临床病理特征和处理相关的变量被分析。Univariate 分析与木头等级测试并且多被执行与考克斯一起的变量分析回归。P【0.05 被认为统计上重要。结果：到女比率的男性是 2.6:1。吝啬的年龄是 60.6 年， 14% 病人比 40 年年轻。腺癌，胃的淋巴瘤，和胃的转移分别地在 94.5% ， 2.3% ，和 3% 病人被发现。有在起始的症状和诊断之间的 6 瞬间延期的一般水准。在腺癌组之中，肠的类型是最普通(55.9%) 并且远侧第三是最普通的本地化(88.4%) 。134 个病人(72.1%) 是男性。31 个病人(17%) 有 GC 的家庭历史。外科在 90% 病人(非药品) 被执行。结论：在南方伊朗的 GC 的流行病学的特征在高风险的区域模仿那些。有在在我们的机构的年轻病人的 GC 的高频率。病人们在相对长的延期以后被检测并且对待。在晚期在场的大多数病人，它赞成差的全面幸存。GC 的家庭历史在我们的区域有一个重要问题。在南方伊朗和更早的诊断和随后的更好的忧虑学习这癌症的病原学被推荐。

AIM： To analyze the characteristics of epidemiological, clinical and survival patterns among patients with carcinoma of the stomach. METHODS： We retrospectively studied the characteristics of 186 gastric adenocarcinoma patients at Ahwaz Jundishapur University Hospitals （AJSUH） from September 1, 1996 to September 1, 2002. All the patients had histopathologically-confirmed malignancy. Demographic variables, family history of gastric cancer （GC）, clinicopathologic characteristics and treatment-related variables were analyzed. Univariate analysis was performed with the log-rank test and multivariate analysis with Cox regression. P 〈 0.05 was considered statistically significant. RESULTS： Male to female ratio was 2.6：1. The mean age was 60.6 years and 14% of the patients were younger than 40 years. Adenocarcinoma, gastric lymphoma, and gastric metastasis were found in 94.5%, 2.3%, and 3% patients, respectively. There was an average of 6-mo delay between the initial symptoms and the diagnosis. Among adenocarcinoma groups, intestinal type was the commonest （55.9%） and the distal third was the most common localization （88.4%）. One hundred and thirty-four patients （72.1%） were males. Thirty-one patients （17%） had a family history of GC. Surgery was performed in 90% of patients （non-curative）. CONCLUSION： The epidemiological features of GC in south Iran mimic those in high-risk areas. There is a higher frequency of GC in young patients at our institution. Patients are detected and treated after a relatively long delay. Most patients present in advanced stages, which favors a poor overall survival, Family history of GC has a significant problem in our area, Studying the etiology of this cancer in south Iran and earlier diagnosis and subsequent better cares are recommended.