Factors predicting poor prognosis in ischemic colitis

瞄准：决定临床、分析、内视镜的因素与有关是化学家大肠炎(IC ) 严厉。方法：85 个病人的一个总数从 1996 年 1 月在回顾的研究被注册到 2004 年 5 月。有 53 女性和 32 男性(年龄 74.6+/-9.4 年，范围 45-89 年) 。病人作为 IC 被诊断。下列变量包括年龄，性别，从到承认的症状的外观的时间的经期，病历，药，凳子频率，临床的症状和症状被分析，验血(血克和基本生物化学的侧面) ，和内视镜的调查结果。病人们在温和 IC 组和严重 IC 组(外科或死亡) 被划分。质的变量用 chi 平方测试被分析，参量的数据用学生的 t (P【0.05 ) 被分析。结果：温和 IC 组 69 个病人被在于(42 女性和 27 男性，平均年龄 74.7+/-12.4 年) 。严重 IC 组由 16 个病人组成(11 女性和 5 男性，平均 73.8+/-12.4 年的年龄) 。因为麦克匪特斯氏疗法(没有外科) 的失败，一个病人死了， 15 个病人经历了外科(6 在内视镜的诊断以后并且 9 在 peroperatory 以后诊断) 。85 个病人(9.6%) 中的八个死了，其它被跟随在上面作为为 9.6+/-3.5 瞬间的门诊病人。人口统计的数据，病历，药和凳子频率在两个组(P】0.05 ) 是类似的。说正经的有病的病人比稍微有病的病人有更少的便血(37.5% 对 86.9% ， P = 0.000 ) 。更多的心悸亢进(45.4% 对 10.1% ， P = 0.011 ) 并且假腹膜炎的更高的流行签名(75% 对 5.7% ， P = 0.000 ) 当腹的疼痛的存在和紧张在二个组之间是类似的时，在严重 IC 组被观察。当承认时，有严重 IC 的二个病人有吃惊。关于分析数据，更严重有病的病人被发现比略微有病的病人有贫血症和血钠过少(37.5% 对 10.1% ， P = 0.014 和 46.6% 对 14.9% ， P = 0.012，分别地) 。狭窄是那比在稍微有病的病人更经常出现在严重有病的病人的唯一的内视镜的发现(66.6% 对 17.3% ， P = 0.017 ) 。结论：能预言 IC 的差的预后是便血，心悸亢进和假腹膜炎，贫血症和血钠过少和狭窄的缺席的因素。

AIM： To determine the clinical, analytical and endoscopic factors related to ischemic colitis （IC） severity. METHODS： A total of 85 patients were enrolled in a retrospective study from January 1996 to May 2004. There were 53 females and 32 males （age 74.6 ± 9.4 years, range 45-89 years）. The patients were diagnosed as IC. The following variables were analyzed including age, sex, period of time from the appearance of symptoms to admission, medical history, medication, stool frequency, clinical symptoms and signs, blood tests （hemogram and basic biochemical profile）, and endoscopic findings. Patients were divided in mild IC group and severe IC group （surgery and/or death）. Qualitative variables were analyzed using chi-square test and parametric data were analyzed using Student＇s t test （P 〈 0.05）. RESULTS： The mild IC group was consisted of 69 patients （42 females and 27 males, average age 74.7 ± 12.4 years）. The severe IC group was composed of 16 patients （11 females and 5 males, average age of 73.8 ± 12.4 years）. One patient died because of failure of medical treatment （no surgery）, 15 patients underwent surgery （6 after endoscopic diagnosis and 9 after peroperatory diagnosis）. Eight of 85 patients （9.6%） died and the others were followed up as out-patients for 9.6 ± 3.5 mo. Demographic data, medical history, medication and stool frequency were similar in both groups （P 〉 0.05）. Seriously ill patients had less hematochezia than slightly ill patients （37.5% vs 86.9%, P = 0.000）. More tachycardia （45.4% vs 10.1%, P = 0.011） and a higher prevalence of peritonism signs （75% vs 5.7%, P = 0.000） were observed in the severe IC group while the presence and intensity of abdominal pain were similar between two groups. Two patients with severe IC had shock when admitted. Regarding analytical data, more seriously ill patients were found to have anemia and hyponatremia than the mildly ill patients （37.5% vs 10.1%, P = 0.014 and 46.6% vs 14.9%, P = 0.012, respectively）. Stenosis was the only endoscopic finding that appeared more frequently in seriously ill patients than in slightly ill patients （66.6% vs 17.3%, P = 0.017）. CONCLUSION： The factors that can predict poor prognosis of IC are the absence of hematochezia, tachycardia and peritonism, anemia and hyponatremia and stenosis.