疟疾儿童血液学分析

Analysis of Hematology Changes in Children with Malaria

目的探讨疟疾患儿外周血三系、血沉及骨髓像变化。方法使用希森美康KX-21血液分析仪检测22例疟疾患儿血细胞,血沉用魏氏法,骨髓进行人工形态学分析。结果疟疾患儿22例Hb<110g/L占68.2%;WBC<4×109/L占41.0%;PLT<100×109/L占77.3%;至少2项低于正常水平占63.6%,3项指标均低占36.4%。血沉增高占95.5%。增生性贫血骨髓像占59.1%,继发性血小板减少骨髓像占77.3%;两者合并占54.5%。结论疟疾患儿外周血3系改变较大。其中PLT和Hb降低最为突出;血沉极大多数增高。骨髓多呈增生性贫血及继发性血小板减少性骨髓像。

Objective To analyze changes of three periodical circulation systems,erythrocyte sedimentation rate and hone marrow cell morphology in children with malaria. Methods The routine tests of hematology by Sysmex KX - 21 Counter, erythrocyte sedimentation rate by Westergren method and hone marrow cell morphology were analyzed. Results In 22 cases of malaria the ratio of Fib level below 110 g/L, WBC below 4 × 10^9/L and PLT below 100 × 10^9/L was 68.2 %, 41.0 %, and 77.3 %, respectively. The ratio of children with all three parameters （Fib, WBC and PLT） abnormal was 36.4%, with two parameters abnormal was 63.6%. Ninty - five point five percent of malaria children＇s erythrocyte sedimentation rate was abnormal. Fifty - nine point one percent of malaria children had hyperplasia anemia bone marrow morphology, 77.3 % .secondary thromhocytopenia and 54.5 % with both of two hone marrow morphology. Conelusions Three periodical circulation systems of malaria children alter notably, especially in PLT and lib. The majority has erythrocyte sedimentation rate abnormal, and hone marrow cell morphology shows hyperplasia anemia and thromhocytopenia.