南京市儿童血铅水平调查及与行为异常关系的研究

Study on the relationship between the abnormal behavior and blood lead level of the children in Nanjing

目的:探讨儿童行为异常与血铅的关系。方法:随机整群抽取南京市2所小学的学龄儿童为对象,所有被选儿童采指端末梢血40μl,血样经消化、离心,采用石墨炉原子吸收分光光度法测定全血中铅含量。血铅水平≥100μg/L为铅中毒组。同时由父母填写Achenbach儿童行为量表(CBCL,艾氏量表)测查儿童行为问题。结果:儿童血铅平均水平为81.2μg/L,男生血铅水平及铅中毒人数显著高于女生,行为异常的儿童血铅水平及铅中毒率明显高于行为正常组。结论:高血铅与儿童行为异常有关,铅对男童的危害高于女童。

Objective： To learn the relationship between the abnormal behavior and blood lead level in children. Methods： Four hundred and four children aged 9-12 years old at 2 primary schools in Nanjing were selected with random cluster sampling. Fortytμl blood was taken from finger for every child and the lead concentration in the whole blood was measured by graphite furnance atom absorption spectrometry after being digested and centrifuge with all blood samples. The children whose blood lead level was over 100μg/L were divided into the lead poisoning group. In the mean time, children＇s behavior was measured by Achenbach behavior checklist, which filled by children＇s parents. Results： It was found that blood lead level in average for the children was 81. 2μg/L; The blood lead level and the numbers of lead poisoning for the boys were more than those for girls, and the blood lead level and the prevalence of lead poisoning for children with abnormal behavior were obviously higher than those for children with normal behavior. Conclusions： There is relationship between high blood lead level and abnormal behavior of children; furthermore, the lead poisoning is more harmful for boys than for girls.