鲍恩样丘疹病研究进展

Advances in the Research of Bowenoid Papulosis

鲍恩样丘疹病为外生殖器部位的多发扁平丘疹,组织病理为低度恶性原位癌表现。研究发现,人乳头瘤病毒与鲍恩样丘疹病关系密切。一些新的治疗方法,如局部免疫调节剂和光动力疗法有显著的优越性。少数皮损有癌变的可能,应终身随访。

Bowenoid papulosis is a disease clinically manifested by multiple flat papules on external genitalia. Histopathologically, it demonstrates low grade of carcinoma in situ. A close relationship between bowenoid papulosis and human papillomavirns has been implicated in researches. Some new approaches, e.g. , local immunomodulators and photodynamic therapy, have shown significant superiority in the treatment of bowenoid papulosis. A few lesions have possibility to progress into malignancy, and such patients should be followed uo for life time.