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环氧化酶-2及其抑制剂在前列腺癌中的研究进展 被引量:7

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摘要 环氧化酶是前列腺素合成过程中一个重要的限速酶,目前至少发现有两种同功酶,即COX-1和COX-2。近年来大量研究表明,COX-2与前列腺癌的发生发展密切相关,有望成为前列腺癌防治的靶分子。本文对其生物学特点、在前列腺癌中的研究现状以及COX-2抑制剂在前列腺癌防治中的应用前景进行综述。
作者 刘久华 张炜
出处 《国际泌尿系统杂志》 2006年第5期662-666,共5页 International Journal of Urology and Nephrology
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