缺血性脑卒中病因分型与临床分型的关系

The study of relationship between etiological and clinical classifications in acute stage of ischemic stroke

目的探讨缺血性脑卒中急性期的病因分型与临床分型是否有关。方法回顾性调查急性缺血性脑卒中患者226例,分别在急性期行临床分型,和完善辅助检查后行病因分型,通过统计学处理了解二者是否相关。结果早期的临床分型与病因分型有关(P=0.012),其中,完全前循环梗死中有44.12%的患者具有颅内大动脉的异常,而腔隙性梗死中病因为小动脉闭塞的占48.72%,未发现部分前循环梗死与病因的明确关系。结论缺血性脑卒中急性期的临床分型能部分预示病因,指导临床诊治。

Objective To verify the relationship between etiological and clinical classifications in acute stage of ischemic stroke. Methods 226 patients admitted during Jan 2002 to July 2002 who were diagnosed as acute ischemic stroke or TIA were retrospectively investigated. The OCSP（Oxfordshire Community Stroke Project） classification of acute stage and TOAST（Trial of Org 10172 in Acute Stroke Treatment）classification were analyzed and the relationship between OCSP and TOAST classifications was investigated. Results OCSP classification of acute stage was related with etiology （ P = 0.012）, especially TACI （total anterior circulation infarct） and LACI （lacunar infarct）. TACI was related with intracranial large artery disease and LACI with small vessel disease. However, the relationship between PACI （partial anterior circulation infarct） and etiology was not found. Conclusions The OCSP classification of acute stage of ischemic stroke is helpful to indicate etiology of ischemic stroke and to direct the diagnosis and treatment in clinical work.