无锡地区解脲支原体药物敏感性分析

Study on Drug Sensitivity of Ureaplasma Urealyticum in Wuxi Region

目的比较9种抗生素对泌尿生殖道解脲支原体(UU)的体外抗菌作用。方法采用体外培养的方法,对410例UU阳性的泌尿生殖器感染患者做药物敏感试验,检测UU对抗生素的耐药性。结果对UU敏感的药物分别是原始霉素(95.85%)、交沙霉素(94.88%)、强力霉素(94.88%)、四环素(88.29%)。UU对环丙沙星、氧氟沙星、红霉素、阿奇霉素的耐药率分别是68.29%、48.29%、24.63%、21.46%。结论泌尿生殖道UU的耐药性监测对指导临床治疗具有重要意义。

Objective To detect ureaplasma urealytieum（UU） in urogenital specimens and study the resistance of UU to nine kinds of antibiotics. Methods By culture in vitro, the drug sensitive tests of UU from 410 patients with UU positive were condueted, Results The sensitive antibiotics were pristinamyein （95.85%） ,Josamyein（94.88% ）,doxyeyeline （94.88%） and tetracycline （88.29%）, respectively. The resistance rates of the tested mycoplasma against ciprofloxacin, ofloxacin, erythromycin and azithromycin were 68.29 %, 48.29 %, 24.63 % and 21.46 %, respectively. Conclusions The monitoring of drug resistance of UU in urogenital specimens is important for clinical treatment.