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原发性硬化性胆管炎发病机制及治疗研究进展 被引量:2

Progress in the research of pathogenesis and therapy of primary sclerosing cholangitis
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摘要 原发性硬化性胆管炎(PSC)是以肝内外胆管进行性炎症、阻塞和纤维化为特征的慢性胆汁淤积性肝病,该病可能是在遗传易感性基础上,由体液和细胞免疫异常介导,胆道上皮对肠道炎症的异常反应,进而导致炎症、纤维化发生。近年来应用大剂量熊去氧胆酸及联合免疫抑制剂治疗PSC取得了令人鼓舞的成果,有望改变疾病预后。肝移植仍是终末期患者首选方案。
出处 《实用医院临床杂志》 2006年第5期91-92,共2页 Practical Journal of Clinical Medicine
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