彩超引导定位移植肝活组织穿刺检查的安全性评价

Safety evaluation on biopsy with color ultrasound-guided or marked in liver transplant recipients

目的：评价彩超引导定位移植肝脏活组织穿刺检查的安全性。方法：分析2002年4月～2005年12月间，我中心肝脏移植受者中186例次彩超实时引导下肝脏穿刺活检的安全性及与穿刺方法、凝血功能和穿刺次数之间的关系。结果：141例肝穿活检中除1例出现肝内出血合并胆瘘外，未出现任何穿刺相关并发症。结论：凝血功能轻度异常患者进行肝穿刺活检是安全的，而穿刺方法、穿刺次数在本组研究中与肝穿刺活检的安全性无明显相关；彩超引导定位移植肝组织穿刺活检是一种具有较高安全性的诊断方法。

Objective：To evaluate the safety of biopsy guided and marked by color ultrasound in patients underwent liver transplantation. Methods： From Apr 2002 to Dec 2005, 141 liver transplant recipients received biopsies were analyzed retrospectively. The safety of biopsy had been evaluated, as well as the relation with safety and the puncture procedures, clotting function and puncture frequency. Resuits： No puncture-correlated complication had been detected in recipients except one patient with intrabepatic bleed and biliary fistula. Conclusion： Biopsy is safety of recipients with mild clotting abnormalities. However, the puncture procedures and puncture frequency had not attenuated the safety of biopsy after liver transplantation in the cases： These clinical data strongly suggest that biopsy with color ultrasound-guided play a key role in diagnosis with satisfactory safety, biopsy with ultrasound-marked is simpler and easier to operate.