90例紫癜性肾炎临床分析

Clinical analysis on 90 cases of Henoch-Schonlein purpura nephritis

目的:分析过敏性紫癜性肾炎(HSPN)患者临床特点和提示活跃的临床指标。方法:对90例确诊HSPN患者的临床及相关检查进行分析,并按照尿蛋白定量进行分组比较。结果:就诊时尿蛋白定量大于1g/天的患者占64.44%,肾病综合征占27.78%,持续性肉眼血尿常伴更严重的蛋白尿和低蛋白血症,随尿蛋白的增加,伴白细胞尿的比例增加。结论:青少年和成人HSPN临床表现多样,伴消化道症出血比例较高;随着尿蛋白增加,临床表现也逐渐加重。持续性肉眼血尿和白细胞尿提示HSPN病变严重且具有活动性。

Objective： To analyze the clinical characteristics of Henoch-Schonlein purpura nephritis（HSPN）. Methods： The clinical data of 90 HSPN patients were analyzed. Results： The patients with proteinuria over 1 gram per day and those with nephritic proteinuria accounted for 64.44% and 27.78%, respectively. Persistent gross hematuria often accompanied severe proteinuria even nephritic syndrome. Leucocyturia prevalence increased while the proteinuria became severe. Conclusion： Adolescent and adult HSPN have many clinical presentations with high index of gastral bleeding. The clinical presentations are getting worse with the increasing profile of proteinuria. Persistent gross hematuria and leucocyturia may reflect the severity and activity of HSPN.