视听功能整合效应同步诱发电位的初步研究

A Preliminary Investigation of Auditory and Visual Neural Function Integration Mechanism:A Synchronous Evoked Potential Study

目的应用视听同步诱发电位技术探索成年人视听神经功能整合的电生理特性。方法分别于视听同步诱发电位的同步程序下,同步测试闪光视觉诱发电位(flash visual evoked potential,FVEP)和听性脑干反应(au-ditory brainstemresponse,ABR),以及同步程序下单独记录ABR,对10名正常成人(20眼和20耳)进行检测并比较:①同步程序下同步测试ABR与同步程序下单独记录ABR的变化;②不同声音刺激强度时同步程序下的FVEP变化特点。结果①同步程序下同步测试ABR与同步程序下单独记录ABR比较,70dB nHL短声刺激时,前者波Ⅴ潜伏期、Ⅰ-Ⅴ、Ⅲ-Ⅴ波间期较后者延长(P<0.05);但短声刺激强度为30、50dB nHL时,ABR各波潜伏期差异无统计学意义(P>0.05);②不同声音刺激强度时同步程序下FVEP N1、P1、N2波潜伏期,N1-P1、P1-N2振幅差异无统计学意义。结论在视听信号整合输入过程中,视听信号进入大脑是有序性:存在视觉信号对听觉信号的时间指导性(影响潜伏期),以期达到信息内环境的稳定性。

Objective To explore the electrophysiological properties of auditory - visual neural function integration in the adults using the auditory - visual synchronous evoked potential. Methods The auditory - visual synchronous evoked potential was measured in 10 normal adults （20 eyes and 20 ears）. Under the program of synchronous evoked potential, two aspects were detected：①The different properties of auditory brainstem response （ABR） at the fixed flash visual stimulation. ②The different properties of flash visual evoked potential （FVEP） at sound stimulation with different level. Results ①At 70 dB nHL click stimulation, wave Ⅴ latency, Ⅰ-Ⅴ、Ⅲ-Ⅴ interwave latencies were prolonged （ P 〈 0.05） while FVEP was not. In contrast, at 30, 50 dB nHL, wave Ⅰ ,Ⅲ, Ⅴ latency and Ⅰ - Ⅲ, Ⅲ - Ⅴ , Ⅰ - Ⅴ interwave latencies showed no significant difference （ P 〉 0.05）.② No significant difference was shown in wave N1 ,P1 -N2 latency of FVEP at different synchronous sound stimulus levels （30,50,70 dB nHL）. Conclusion The changes of latency indicate that visual signals influence the entry time of auditory signals so as to maintain the stability of inner information environment. In the input process of the auditory - visual integration information, the auditory and visual signals may be delivered in sequence：a probable visual priority phenomenon is suspected.