鸡從多糖的分离及其性质研究

STUDIES ON ISOLATION AND CHARACTERIZATION OF POLYSACCHARIDE OF TERMITOMYCES ALBUMINOSUS

用热水抽提乙醇沉淀的方法从鸡從菌[Termitomyces albuminosus(Berk)Heim]子实体获得了一种灰白色多糖,其总糖含量为77.35% ,蛋白质含量9.14％。生物学研究表明:鸡（土从）多糖[TP]能促进机体免疫功能,增加胸腺、脾脏器官重量,ip 100ug/kg。天剂量,可使正常小白鼠外周血中白细胞总数增加33.69％,使红细胞中SOD酶活性显著升高,体外对脾淋巴细胞的转化也有显著的促进作用。

A grey polysaccharide was precipitated from the hot water extract of fruiting body of Termitomyces albuminosus by addition of ethanol. The content of total sugar and protein were 77.35% and 9.14% respectively. Studies on biological characterization identified that Termitomyces albuminosus polysaccharide(TP) promoted the immune activity of white mice, increased the weight of thymuses and spleen . Treated with the dose of 100ug/ml/day by ip, the TP enhanced leucocyte number of peripheral of normal white mice by 33.6%, improved the activity of supperroxide dismutase (SOD) within reythrocytes outstandingly; it also took a significant cheek on spleen lymphocytes transformation in vitro.