反相高效液相色谱法对间苯二甲酸二羟乙酯5－磺酸钠合成的控制

Determining the Conversion Rate in Synthesis of 5-Sodium Sulfobis (Hydroxyethyl) Isophthalate by HPLC

提出了利用Ｃ１８色谱柱，以含有烷基磺酸盐的甲醇／水溶液为流动相，对阳离子染料可染聚酯用第三单体合成体系主成分进行快速分析测定的色谱方法．以该方法测定结果为依据计算的第三单体转化率比原有测定方法准确、快速．该测定方法提供的数据为准确控制反应的深度提供了可靠依据．

This paper introduces a method for determining the conversion rate in synthesis of 5-sodium sulfobis (hydroxyethyl) isophthalate by HPLC. It is carried out with a YWGC18 Column of 4. 6 mm × 200 mm, using methanol water (25: 75 v/v) and sodium alkyl'sulfonate as mobile phase at a flow rate of l mL. /min. The detection wave length of UV is 230 urn. This method is quicker and more exact than the normally used method.