射频子宫内膜消融术治疗功能失调性子宫出血的临床探讨

An exploratory study on clinical application of radiofrequency endometrium ablation in treatment for dysfunctional uterine bleeding

目的探讨射频子宫内膜消融术(RFEA)治疗功能失调性子宫出血的临床疗效及疗效影响因素。方法选择自愿接受 RFEA 治疗的功能失调性子宫出血患者108例为研究对象,在 B 超监视和引导下将射频自凝刀经阴道宫颈置入子宫腔行宫内膜自凝固治疗。结果治疗后随访6～12个月,随访104例,治疗总有效率为94.4%(102/108),治愈率即闭经率45.3%(49/108),贫血纠正率94.9%(75/79)。结论 RFEA 是治疗功能失调性子宫出血安全有效的微创方法;规范操作是提高疗效的关键。

Objective To study effectiveness of clinical application of radiofrequency endometrium ablation （RFEA） in treatment for dysfunctional uterine bleeding （DUB） and its related factors. Methods One hundred and eight cases of DUB with voluntary acceptance of RFEA were involved in the study. A highfrequency electric auto-coagulating knife was inserted into uterine cavity via vagina and cervix under monitoring and guidance of B-type ultrasonography. Results All the patients of DUB were followed up for 6 to 12 months after RFEA, and 102 of them were effective, with an overall curative rate of 94.4 percent （102/108）. Forty-nine of them were amenorrhea, with a curative rate of 45.3% （49/108）. Anemia was cured in 75 of 79 patients, with a ratio of 94.9% （75/79）. Conclusion RFEA was a reliable and safe method with micro injury in treatment for DUB. Standardization of operative procedures was critical to improve its treatment efficacy.