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幽门螺杆菌感染与胃炎粘膜中氨基巳糖含量的关系

Gastritis with Helicobater Pylori(HP) Infection and Gastric Mucosa Hexosamine concentration
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摘要 本文作者对46例经纤维胃镜和组织病理学诊断的慢性胃炎患者,进行了粘膜的幽门螺杆菌(Helicobacterpylori,HP)尿素酶试验和病理Giemsa染色检查及粘膜中氨基巳糖的测定。发现HP阳性胃炎病人的胃粘膜中,其氨基巳糖含量较HP阴性胃炎组明显降低。分别为30.34±5.56μg/mg湿重和56.86±6.92μg/mg湿重。经德诺治疗HP阴转后,胃炎好转,氨基巳糖含量明显回升。揭示氨基巳糖测定对研讨HP相关性胃炎的发生、转归有重要价值。 The purpose of this study was to evalute the relation-ship between gastric mucosa hexosamine and chronic gastritis. Gastric mucosa hexosamine concentration was 30.34±5.56μg/mg wet tissue in 30 HP positive gastritis.The concentration was significantly lower in HP positive gastritis than in HP negative gastritis (n=16, 56.86±6.92μg/mg wet tissue, p<0.05). Gastric mucosa hexosamine concentration increased in 6 gastritis cases after cleanance HP with De-Nol. (fron 28.18±5.79 to 64.35±8.12μg/mg wet tissue). The improvement in gastritis and disappearance of HP after treatment with De-Nol might contribute to the increase of gastric mucosa hexosamine. The data indicated that HP exert significant action on the gastric inflammation.
出处 《华西医学》 CAS 北大核心 1996年第4期373-374,共2页 West China Medical Journal
关键词 幽门螺杆菌 氨基巳糖 胃炎 gastritis, helicobater pylori, hexosamine, De-Nol.
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