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高血压合并代谢综合征患者大动脉顺应性变化的探讨

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摘要 目的探讨高血压合并代谢综合征(MS)患者大动脉顺应性的变化。方法检测118例Ⅰ~Ⅱ级高血压患者和66名对照者颈-股动脉的脉搏波速度(C—FPWV),同时检测其身高、体重、腰围、臀围、血压、血糖、血脂水平,并计算体重指数(BMI)、腰臀比(WHR)。结果高血压合并MS患者、单纯高血压患者C—FPWV和对照组相比较明显升高(10.21.4m/s±1.4m/s、9.71.4m/s±1.5m/s与8.31.4m/s±1.3m/s,P〈0.01)。高血压合并MS患者与单纯高血压患者相比升高(10.21.4m/s±1.4m/s与9.71.4m/s±1.5m/s,P〈0.05)。Peasion相关分析显示脉博波速度(PWV)与所检测各指标除HDL—C外,其余均呈显著正相关(P〈0.01)。结论高血压合并MS患者C—FPWV明显升高,已经存在动脉顺应性的减退,且其大动脉顺应性的变化与年龄、血压、肥胖和血脂紊乱有关。
出处 《临床内科杂志》 CAS 2006年第9期631-633,共3页 Journal of Clinical Internal Medicine
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