乙酰唑胺治疗脑血管病后顽固性呃逆的疗效观察

Investigation to the effect of diamox for intractable hiccup after cerebrovascular diseases

目的观察乙酰唑胺对脑血管病后顽固性呃逆的疗效。方法43例顽固性呃逆患者随机分为2组，其中治疗组23例（男10例，女13例）采取乙酰唑胺治疗，0．25～0．5g，口服3a／d，疗程3～5d。对照组20例（男8例，女12例）采用氯丙嗪25mg，口服3次／d，辅以针灸治疗．疗程3～7d。结果治疗组总有效率100％，对照组总有效率50％（P〈0．01）．治疗组起效快，不良反应少。结论乙酰唑胺是治疗顽固性呃逆较为有效的药物。

Objective To investigate the effect of diamox for intractable hiccup alter cerebrovascular diseases. Metnods 46 patients were randomized into two groups. 23 cases were in treatment group （10 cases of males, 13 cases of females）,who were given diamox to take orally,0.25-0.5 g,three times per day,for 3-5 days. 20 patients were in control group（8 cases of males, 20 cases of females）, who were given chlorpromazine to take orally, 25 mg,three times per day,assisted with acupuncture for 3-7 days. Results The total effective rate of treatment group is 100% ,while the total effective rate of control group is 50% （P〈0.01）. Conclusion Diamox is an effective medicine for intractable hiccup.