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RNA干涉技术 被引量:2

Reacarch on RNA Interference
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摘要 综述RNAi的发展历史,介绍RNA的作用机制及其特点并展望其应用前景。 Double-stranded RNA-mediated RNA interference(RNAi) is one of the process of sequence-specific post-transcriptional silencing gene. The discovery, characteristic, machanism and application of RNAi were discussed in this paper.
作者 何平 张志宏
出处 《安徽农业科学》 CAS 北大核心 2006年第17期4245-4246,共2页 Journal of Anhui Agricultural Sciences
关键词 RNA干涉 基因沉默 双链RNA RNA interference Gene-silenchag Double-stranded RNA
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参考文献14

  • 1FIRE A,XU S,MONTGOMERY M K,et al.Potent and specifec genetic interferenceby double-stranded RNA in caenorhabditis elegans[J].Nature,1998(391):806-811.
  • 2ROMANO N,MACION G.Quelling:transient inactivation of gene expression in Nenrospora crassa by transformation with homologous sequences[J].MOL Microbiol,1992(6):3 343-3 353.
  • 3HAMMOND S M,CAUDY A A,HANNON G J.Post-transcriptianal gene silencing by double-stranded RNA[J].Nature Rev Gen,2001(2):110-119.
  • 4COGONI C,MACINO G.Post-transcriptional gene silencing across kingdoms[J].Genes Dev,2000(10):628-643.
  • 5ELBASHIR S M,LENDECKEL W,TUSCHL T.RNA interference is mediated by21-and 22-nucletiide RNAs[J].Gene Dev,2001(15):188-200.
  • 6BRUMELKAMP TR,BERNARDS R,AGAMI R.A system for stable expression of short interfering RNAs in mammalian cells[J].Science,2002,296(5567):550-553.
  • 7FAGARD M,BOUTET S,MOREL J B,et al.AG0-1,QDE-2and RDE-1 are related protein required for post-transcriptional gene silencing in plants,quelling in fungi and RNAi in animals[J].Proc Natl Acad Sci USA,2000,97(21):11650-11654.
  • 8TUSCHL T,ZAMORE P D,TARGETED M.RNA degradation by double-stranded RAN in Vitro[J].Gene Dev,1999,13(24):3 191-3 197.
  • 9TIMMON L,FIRE A.Specifec interference by ingested dsRNA[J].Nature,1998,395(6705):854.
  • 10JORGENSEN R A,ATLINSON R G,FORSTER R L S,et al.An RNA-based information superhighway in plants[J].Science,1998(279):1 486-1 487.

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