高龄血液透析患者透析充分性及微炎症与营养状态的关系

Influence of Hemodialysis Adequacy and Inflammation on Nutritional Status in Senile Maintenance Hemodialysis Patients

【目的】探讨高龄维持性血液透析(MHD)患者透析充分性、微炎症与营养状态的关系。【方法】测定26例高龄及37例非高龄MHD患者BUN、CRP、ALB、Hb、TF等,并计算Kt/Ve及nPCR;以改良定量主观整体评估(MQ-SGA)表评估患者营养状况。【结果】高龄患者Kt/Ve与nPCR正相关,与MQ-SGA呈负相关;CRP与MQ-SGA正相关。【结论】透析充分性及机体微炎症状态对高龄MHD患者营养状况有重要影响,同等透析剂量下高龄MHD患者更易并发营养不良。

[Objective]To investegate the influence of adequacy of hemodialysis and inflammation on nutritional status in senile maintenance hemodialysis（MHD） patients. [Methods]Serum BUN, CRP, ALB, Hb and TF were assayed in 26 senile and 37 non-senile MHD patients. Nutritional status was assessed by Modified Quantitative Subjective Global Assessment（MQ-SGA）. [Results]There was positive correlation between Kt/ Ve and nPCR and negative correlation between Kt/Vo and MQ-SGA. There was positive correlation between CRP and MQ-SGA in senile MHD patients. [Conclusion] Hemodialysis adequacy affects nutritional status markedly in senile MHD patients. The senile MHD patients have more tendency to malnutrition.