腹腔镜下单极法电消融术治疗子宫腺肌病术后血清CA_(125)水平、EMAb阳性率及性激素水平的变化

Changes of the Levels of Serum CA_(125)、EMAb and Sexual Hormones Both Before and After Laparoscopic Monopole Electromyolysis for the Treatment of Adenomyosis

【目的】探讨腹腔镜下单极法电消融术治疗子宫腺肌病术后血清CA125水平、EMAb阳性率及性激素水平的变化。【方法】对26例子宫腺肌病患者行腹腔镜下单极法电消融术治疗,测定手术前后血癌抗原(CA125)、抗子宫内膜抗体(EMAb)及性激素水平。【结果】术后患者血清CA125水平及EMAb阳性率均较术前显著降低(P<0.01),手术前后促卵泡生成素(FSH)、促黄体生成素(LH)和雌二醇(E2)差异无显著性(P>0.05);所有患者未出现围绝经期症状。【结论】腹腔镜下单极法电消融术可降低血清CA125水平及EMAb阳性率、对性激素影响不大。

[Objective]To investigate the changes of the levels of serum CA125, EMAb and sexual hormones before and after laparoscopic monopole electromyolysis for the treatment of adenomyosis. [Methods] Twentysix cases of adenomyosis were performed with laparoscopic monopole electromyolysis. The levels of serum CA125 ,EMAb and sexual hormones were detected both before and after therapy. [Results] After therapy, the levels of serum CA125 ,EMAb decreased significantly. There was no statistical difference between the measurements of FSH,LH,E2 before and after surgery （ P 〉0.05）. No one appeared to have menopause change. [Conclusion]Laparoscopic monopole electromyolysis may decrease the levels of serum CA125 ,EMAb, but not affect the serum levels of FSH,LH and E2.