112例婴幼儿抗生素相关性腹泻临床分析

The Infant Antibiotic Associated Diarrhea : a Clinical Analysis of 112 Cases

目的:分析婴幼儿腹泻患者抗生素相关性腹泻(antibioticassociateddiarrheaAAD)的临床关联性及发病率,更进一步探讨抗生素应用对腹泻病程的影响,提出预防措施。方法:采用回顾性调查方法,围绕抗生素应用与腹泻的时间关系,对我院近2年来收住的112例AAD患儿进行临床分析。结果:抗生素使用时间≥5d,腹泻发生率明显增加,使用抗生素时间越长,腹泻病程越长;联合使用抗生素种类越多,腹泻发生率越高。结论:合理使用抗生素,严格控制广谱抗生素的使用,是预防和控制AAD的关键。

Objective To investigate the clinical connection and the incidence of the disease of the infant antibiotic associated diarrhea. Further discuss the affect of the course of diarrhea for used antibiotic. Proposes the preventive measure. Methods Used the review investigate methods. The clinical dates of 112 cases of patients of antibiotic associated diarrhea recently two years in our hospital were analyzed round the time relation of antibiotic use and the diarrhea. Results The period of use antibiotic ≥5 days,the formation rate of diarrhea was increased obviously. The period of use antibiotic longer,the course of disease of diarrhea longer and used more kinds of antibiotics,the formation rates of diarrhea were higher. Conclusion Reasonable use antibiotic and control the broad-spectrum antibiotic use strictly are the linchpin measure to prevent and control the antibiotic associated diarrhea.