摘要
目的研究血同型半胱氨酸水平与不稳定型心绞痛的关系。方法随机选取90例不稳定型心绞痛患者,并以90例健康对照为对照,观察不稳定型心绞痛与同型半胱氨酸血症的关系。结果不稳定型心绞痛组血同型半胱氨酸水平明显高于对照组(P<0.05)。Logistic回归分析显示,排除高血压、糖尿病、高血脂、吸烟史、冠心病家族史等因素,受试者的不稳定型心绞痛发生率与高血同型半胱氨酸水平有相关性(OR=1.631,95%CI1.0,2.8)。结论高同型半胱氨酸血症是不稳定型心绞痛发病的危险因素。
Objective To study the correlation between hyperhomocysteinemia and unstable angina pectoris. Methods The correlation between hyperhomocysteinemia and unstable angina pectoris was studied in 90 cases with unstable angina pectoris and 90 healthy subjects as controls. Results Homocysteinemia in unstable angina pectoris patients was significantly higher than in controls（ P 〈 0.05）. Multiple logistic regression analysis showed hyperhomocysteinemia was significantly correlated with unstable angina pectoris, ecluding hypertension, diabetes, hyperlipidemia,history of smoke and coronary heart disease （ OR = 1. 631,95% CI1.0- 2.8 ）. Conclusion Hyperhomocysteinemia is a risk factor for unstable angina pectoris.
出处
《中国医药》
2006年第10期577-578,共2页
China Medicine
基金
广东省深圳市科技信息局项目(2005025)
关键词
冠心病
不稳定型心绞痛
同型半胱氨酸
危险因素
Coronary heart disease
Unstable angina pectoris
Homocysteinemia
Risk factor
