我国药品不良反应相关文献分析

Literature analysis on Adverse Drug Reaction in China

目的了解我国药品不良反应报告与监测的现状与趋势,为药品不良反应监测工作者提供参考。方法以“不良反应”为关键词,在所选定的5种药学类期刊中检索篇名含有“不良反应”的文献,对2000～2005年的有关文献进行统计、分析。结果作为药品不良反应研究基础的病例报告,近年来其数量仍然是所有药品不良反应文献中最多的,平均占48.62%;研究性论文的数量占同期所有药品不良反应文献数量的百分比由2000～2002年的9.33%上升至2004～2005年的20.92%。结论近年来,我国药品不良反应报告与监测工作进展显著,药品不良反应研究工作正在逐步展开。

Objective To find out the actuality and trend of ADR report and monitoring, and supply information to ADR staffs. Method To search 5 core journals on pharmaceutical in the Chinese journal fulltext database using ADR as the key words, classify and analyze the literature on ADR published from 2000 to 2005. Result Case reports, as the basis of ADR research, still have the largest number of literature in recent years, accounted for 48.62% on average. The number of research literature accounts for 9.33% during 2000 to 2002 and rise to 20.92% during 2004 to 2005. Conclusion ADR monitoring has made obvious progress and ADR research has been carried out in recent years.