黄芪加百令治疗小儿原发性肾病综合征的临床观察

Clinical efficacy anylysis of Astragalus and Bailting on Preventing Childrens In itiate Nephropathy Syndrome

目的观察黄芪加百令在治疗小儿原发性肾病综合征中的作用。方法将56例原发性肾病综合征患儿随机分为对照组和观察组,两组均常规应用泼尼松和潘生丁,观察组加用黄芪加百令,随访12～24个月。结果治疗前两组患儿的IgA、IgM、IgG间差别均无显著性意义(P>0.05),治疗后除IgM外,IgA、IgG间差别均有显著性意义(P<0.05);两组患儿的复发率间差别有显著性意义(P<0.05)。结论在常规应用激素和口服潘生丁的基础上,加用黄芪加百令对小儿原发性肾病综合征的治疗和预防复发有一定的效果。

Objective To observe the curative effect of astragalus and Bailing on preventing the relapse of child in itiate nephropathy, Methods 56 children who all suffered from the Initiate nephropathy were randomly allocated two groups. One is the control group in cluding 31 children, only taking oral prednisone and persanfine. The other is the intervention group including 25 children who take astragalus and Baiking besides prednisone and persantine. They were medical observed in next 12～24 months. Results There is no obvious significance among IgA, IgM and IgG in the two groups before the treatment. After the treatment, there is significant difference in relapse rate of the two groups. Conclusions Astragalus ＆ Bailing with prednisone and persantine has some curative effect on preventing the relapse of child initiate nephropathy.