摘要
目的探讨脐带血血气分析及乳酸值对围产期窒息的诊断价值。方法对63例足月窒息新生儿与89例足月正常新生儿的脐动脉血进行微量血气分析及乳酸测定,并在出生后第1、7、14、28d进行新生儿20项神经行为测定(NBNA)。结果窒息组与对照组的脐动脉血乳酸、pH值、BE差异有显著性,血乳酸与第1、7d的NBNA呈显著负相关,pH与第1d的NBNA呈正相关,BE与NBNA无明显相关性。结论窒息新生儿脐血乳酸水平高于对照组、pH值低于对照组,可作为围产期窒息诊断的指标,且乳酸值特异性优于pH值。
Objective To investigate the diagnostic value of cord blood gas and lactate in perinatal asphyxia. Methods Umbilical artery blood gas and lactate were measured in 63 term newborn infants with perinatal asphyxia and 89 normal term newborn infants. Each of them was examined with 20-item Neonatal Behavioral Neurological Assessment （NBNA） in 1,7,14 and 28 days after birth. Results Umbilical arterial blood lactate,pH,BE were significantly different in asphyxia group and control group. The level of lactate correlated negatively with NBNA at 1 and 7 days. The pH correlated positively with NBNA at 1 day. Conclusions Lactate level increases in neonates with perinatal asphyxia and correlates negatively with NBNA. As an indicator of perinatal asphyxia, lactate is better than pH.
出处
《中国新生儿科杂志》
CAS
2006年第4期193-196,共4页
Chinese Journal of Neonatology
基金
湖南省卫生厅科研基金资助项目(编号:Y02055)
