摘要
目的:观察鱼腥草注射液对慢性阻塞性肺疾病(COPD)急性加重期患者炎症细胞因子与肺功能的影响。方法:将80例患者随机分为两组,均予西药常规治疗,治疗组加用鱼腥草注射液。分别于治疗前后观察两组白介素-8(IL-8),肿瘤坏死因子(TNF-α)及第1秒用力肺活量(FEV1),用力肺活量(FVC)及FEV1/FVC的变化。结果:治疗组IL-8、TNF-α明显下降,显著优于对照组,FEV1、FVC、FEV1/FVC较对照组明显提高(P<0·05)。结论:鱼腥草注射液能有效降低炎症细胞因子,改善肺功能,与西药合用于COPD急性加重期能取得更好的疗效。
Objective: To observe the effects of houttuynia injection on inflammatory cellular factors and pulmonary function of patients at acute stage of chronic obstructive pulmonary disease. Methods: 80 cases were divided into two groups at random, both were given western medicine, the treatment group were given houttuynia injection at the same time. The changes of IL-8, TNF-a, FEV1, FVC and FEV1/FVC were tested. Results: The levels of IL-8 and TNF-a were significantly lower than those in control (P<0.05), FEV1, FVC and FEV1/FVC got higher obviously than those of control (P<0.05). Conclusion: Houttuynia injection can effectively lower inflammatory cellular factors, improve pulmonary function of patients with chronic obstructive disease.
出处
《中国中医药科技》
CAS
2006年第5期294-295,共2页
Chinese Journal of Traditional Medical Science and Technology
基金
成都市科委重点科技计划项目No.2002-67
