摘要
目的为阐明清肺愈痤丸治疗寻常痤疮的作用机理。方法采用金黄地鼠背部两侧肋部皮脂腺斑作为动物模型,观察皮脂腺斑大小及显微结构。结果清肺愈痤丸能够使皮脂腺斑萎缩,松散,变薄,与维胺脂治疗组统计学上无显著性差异(P>0.05)。结论清肺愈痤丸具有抑制皮脂腺增生作用,是其治疗寻常痤疮机理之一。
Objective To study the pharmacodynamics of Qingfeiyucuopills. Methods Observed the longest traverse diameter and the longest longitudinal diameter , and the microstructure of the the Syrian Hamsters flank organ. Results： Middle dosage group, big dosage group, and Retinamidoester group had effect on the flank organs（P 〈0. 05）. The effect of big dosage group on the flank organs was equal to that of Retinamidoester group（ P 〉 0.05 ）. Middle dosage, big dosage, and Retinamidoester could significantly decreased thickness of flank organs（ P 〈 0. 05 ）. Conclusion： it can restrain function of flank organs, and influence hyperplasia of flank organs .
