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脑缺血再灌注损伤的病理生理研究进展 被引量：23

Recent Advances in Pathophysiology Mechanisms of Cerebral Ischemic Reperfusion Injury
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摘要 脑缺血再灌注损伤是一复杂的病理生理过程,这个级联反应包括许多环节,如能量障碍,细胞酸中毒、兴奋性氨基酸释放增加、细胞内钙失稳态、自由基生成、炎性细胞因子的释放、凋亡基因激活等。本文就脑缺血再灌注损伤有关的病理生理研究进展做一综述。 Cerebral ischemical reperfusion injury is a complex pathophysiological process, there are many links in this cascade reaction, including, cellular acidosis, increased releasing of excitatory amino acid, destabilization of intracellular Ca2 ＋ , production of free radicle, releasing of inflarmmatory cytokines and activation of apoptosis gene. This review provides an overview of recent advances in pathophysiology mechanisms of eerebral ischemical reperfusion injury.
作者 方舒东 朱也森
机构地区 上海交通大学附属第九人民医院麻醉科
出处 《医学综述》 2006年第18期1114-1116,共3页 Medical Recapitulate
关键词 脑缺血再灌注 机制研究 病理生理 Cerebral isehemieal reperfusion Study of Mechanism Pathophysiology
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献17

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二级参考文献25

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共引文献37

同被引文献282

引证文献23

二级引证文献91

医学综述
2006年 第18期

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