脉冲振荡肺功能测定在学龄前期儿童哮喘治疗中价值

THE VALUE OF MEASUREMENT OF PULMONARY FUNCTION BY IMPULSE OSCILLOMETRY IN THE TREATMENT OF ASTHMA IN PRESCHOOL CHILDREN

目的探讨脉冲振荡肺功能（IOS）测定在学龄前期儿童哮喘治疗中的应用价值。方法应用Master Screen系列肺功能测定系统，对不能配合完成常规肺功能（PFT）测试的学龄前期不同病期哮喘病儿（发作组32例，缓解组30例）及正常对照儿童（20例）进行IOS测试。结果所有儿童全部完成测试。发作组与缓解组比较，除R20外，R5、R5—R20、X5、Fres、Zrs各指标差异皆有显著性（F=6．51～14．42，q=6．02～8．80，P〈0．01）。缓解组R5—R20、Fres与对照组比较差异有显著性（q=5．98、6．04，P〈0．01）。发作组除R5、R5-R20、Fres外，其余指标异常率与缓解组比较，差异均具有极显著性（x^2=14．60～28．61，P〈0．01）。结论学龄前期儿童哮喘IOS测试有很好的可行性，IOS测定可作为哮喘病儿治疗评价中的很好的手段。

Objective To assess the value of impulse oscillometry （IOS） for pulmonary function test in the treatment of asthma in preschool children. Methods Children under the asthma attack （32 cases）, in remission （30） and healthy children （20） were tested by IOS via Master Screen System. Results Significant differences were found between the children under the asthma attack and in remission, in terms of R5, R5-R20, X5, Fres and Zrs （F= 6.51- 14.42, q = 6.02- 8.80, P〈0.01）. Significant differences of above items were also noted between the children in remission and the healthy ones （q= 5.98,6. 04; P〈0.01）. Conclusion IOS is a good method in evaluation of the treatment of preschool children with asthma.