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氟哌啶醇对多发性抽动症病儿甲状腺功能的影响 被引量:1

EFFECTS OF HALOPERIDOL ON FUNCTION OF THYROID IN CHILDREN WITH TOURETTE SYNDROME
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摘要 目的探讨氟哌啶醇对多发性抽动症(TS)病儿甲状腺功能的影响。方法将56例TS病儿随机分为用药组35例和对照组21例,采用放射免疫分析法(RIA)进行血清TSH、FT3、FT4水平测定。结果氟哌啶醇对TS病儿TSH、FT3、FT4水平无明显影响(P>0.05),用药时间长者TSH、FT4浓度较高,但也无显著性差异(P>0.05)。结论氟哌啶醇对多发性抽动症病儿甲状腺功能无明显影响。 Objective To evaluate the effects of Haloperidol on the function of thyroid in children with Tourette syndrome (TS). Methods Fifty-six children with TS were randomly divided into two groups: Haloperidol-treated group (n=35) and control group (n= 21), and their serum concentrations of TSH, FT3 and FT4 were measured by RIA technique. Results No obvious effect of Haloperidol on TSH, FT3 and FT4 was noted (n=35) as compared with that of control group (n= 21)( P〉 0. 05). Though the values of TSH and FT4 were higher in those treated longer, the difference was not statistically significant (P〉 0.05). Conclusion Haloperidol may have no significant influence on the function of thyroid in children with Tourette syndrome.
出处 《齐鲁医学杂志》 2006年第6期515-516,共2页 Medical Journal of Qilu
关键词 抽搐性运动障碍 氟哌啶醇 甲状腺激素类 tic disorders Haloperidol thyroid hormones
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参考文献3

  • 1叶秀云,胡鸿文.苯巴比妥、苯妥英、卡马西平对癫痫患儿甲状腺激素的影响[J].中华儿科杂志,1998,36(10):624-624. 被引量:7
  • 2EGGERS C,ROTHENBERGER A,BERGHAUS U.Clinical and neurobiological findings in children suffering from tic disease following treatment with tiapride[J].Eur Arch Psy Neurol Sci,1988,237:223.
  • 3MGLIOZZI J R,GOLD A,LAUBLY J N.Effect of oral administration of haloperidol on plasmathyrotropin concentration in men[J].Psychoneuroendocrinology,1989,14(1/2):125-130.

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