病原未定型肝炎的临床研究

Clinical research of cryptonenic hepatitis

目的 探讨病原未定型肝炎的临床特征。方法 以43例慢性乙型肝炎和30例急性乙型肝炎为对照组，对62例病原未定型肝炎患者进行临床分析，比较病原未定型肝炎的流行病学、临床表现、实验室检查及肝组织学改变。结果 62例病原未定型肝炎患者发病以冬末及春季多见；发病年龄以青、中年（18岁～50岁）占92．2％；临床表现有急性和慢性，多数症状轻、肝病体征少；血清转氨酶水平呈轻、中度升高；肝活检组织病理学显示炎症轻；绝大多数预岳良好。结论 病原未定型肝炎的致病因子仍不清楚。

Objective To study the clinical features of undefined hepatitis. Methods In comparison with chronic hepatitis B （n=43） and acute hepatitis B （n=30） , 62 cases with undefined hepatitis were analyzed clinically. The epidemiology, clinical manifastation, laboratory test , and pathological features in liver tissues were analyzed . Results The clinical features of undefined hepatitis were more common in spring and late winter： The incidence of the youth and the middle-aged was about 92.2%; There might be acute or chronic ; The symptoms and signs were slight; Serum alanine aminotransaminase levels elevated mildly or modestly： The liver tissues inflammation activity was mild; The prognosis was favourable. Conclusion The cause of undefined hepatitis needs further elucidated.