摘要
目的为了进一步研究与发展均三嗪衍生物的制备方法。方法在丙酮介质中,三聚氯氰先后与N-甲基苯胺、乙醇反应,合成了N-甲基苯氨基-4,6-二乙氧基-1,3,5-三嗪。结果标题化合物经红外光谱和质谱对它进行了表征。在最佳的工艺条件即,三聚氯氰3.7g,N-甲基苯胺2mL,乙醇30mL;反应温度:第一步反应温度为0~5℃,反应时间为0.5h;第二步反应温度为28-32℃,反应时间为4h;滴加速度均为0.5~1mL·min^-1时,目标产物收率为75%。结论制备方法简单,反应条件温和,效果良好。
Aim To study and develop synthetic methods of 1,3,5-triazine derivatives further. Method In the medium of acetone, N-methyl-phenylamino-4,6-diethoxy-l,3,5-triazine had been prepared by the reaction of cyanuric chloride, N-methylaniline and ethanol. Results The product has been characterized by IR and MS. In the optimum conditions, the required amount of cyanuric trichlo- ride is 3.7 g, N-methyl-phenylamine is 2 mL, and ethanol is 30 mL. At the first step, the reaction temperatue is 0 5 ℃ and the reaction time is 0. 5 h; secondly, the reaction temperatue is 28 - 32℃C and the reaction time is 4 h. In addition, the dropping speed is 0.5-1 mL·min^-1 and the desired product was present in the yield of 75%. Conclusion This method is simple with mild reaction conditions and good effect.
出处
《宝鸡文理学院学报(自然科学版)》
CAS
2006年第3期193-195,共3页
Journal of Baoji University of Arts and Sciences(Natural Science Edition)
基金
江西省自然科学基金资助项目(No.0520083)
江西省教育厅科技计划项目(赣教技字06268)