N-甲基苯氨基-4,6-二乙氧基-1,3,5-三嗪的合成与表征

Synthesis and characterization of N-methyl-phenylamino-4,6-diethoxy-1,3,5-triazine

目的为了进一步研究与发展均三嗪衍生物的制备方法。方法在丙酮介质中，三聚氯氰先后与N-甲基苯胺、乙醇反应，合成了N-甲基苯氨基-4，6-二乙氧基-1，3，5-三嗪。结果标题化合物经红外光谱和质谱对它进行了表征。在最佳的工艺条件即，三聚氯氰3．7g，N-甲基苯胺2mL，乙醇30mL；反应温度：第一步反应温度为0～5℃，反应时间为0．5h；第二步反应温度为28-32℃，反应时间为4h；滴加速度均为0．5～1mL·min^-1时，目标产物收率为75％。结论制备方法简单，反应条件温和，效果良好。

Aim To study and develop synthetic methods of 1,3,5-triazine derivatives further. Method In the medium of acetone, N-methyl-phenylamino-4,6-diethoxy-l,3,5-triazine had been prepared by the reaction of cyanuric chloride, N-methylaniline and ethanol. Results The product has been characterized by IR and MS. In the optimum conditions, the required amount of cyanuric trichlo- ride is 3.7 g, N-methyl-phenylamine is 2 mL, and ethanol is 30 mL. At the first step, the reaction temperatue is 0 5 ℃ and the reaction time is 0. 5 h; secondly, the reaction temperatue is 28 - 32℃C and the reaction time is 4 h. In addition, the dropping speed is 0.5-1 mL·min^-1 and the desired product was present in the yield of 75%. Conclusion This method is simple with mild reaction conditions and good effect.