慢性氟中毒大白鼠肝肾组织学观察

Histopathological Observations on the Liver and Kidney of Rats with Experimental Chronic Fluorosis

给大白鼠自饮含氟量为50ppm和75ppm的水100天,成功地建立了氟对软组织、特别是肝脏和肾脏发生病理改变的慢性氟中毒动物模型。

Animal models of chronic fluorosis with pathologic changes in the liver and kindney were made by feeding wister rats with high fluoride water (50 and 75ppm F-) for 100 days.