慢性肾衰竭心血管并发症及其中医证候分析

Cardiovascular Complications and Its Chinese Medical Syndromes of Chronic Renal Failure

目的探讨慢性肾衰竭(CRF)心血管并发症及其中医证侯分布情况。方法通过临床调研,对CRF并发心血管患者的原发病、中医证型及邪实兼证等规律进行调查分析。结果非透析CRF患者的心血管并发症的总发病率为41.51%,其中慢性肾小球肾炎CRF、高血压肾病CRF、糖尿病肾病CRF并发心血管疾病的比例分别为26.62%、6.92%和5.45%;随着肾功能恶化,心血管并发症的发病率逐步上升,在统计学上具有正相关性;高血压病CRF、糖尿病肾病CRF易并发心血管疾病,其发病率分别为64.71%和60.47%;男、女两性在CRF患者心血管并发症中的发病率无明显差异。CRF心血管并发症以脾肾阳虚型最常见(87.50%),具有邪实(湿、瘀)兼证的患者总比例为92.93%。结论提示CRF心血管并发症在病机上存在以CRF为基础的转化规律,终至形成阳微阴弦、本虚标实的病理状态,而瘀湿毒等邪实加速和诱发了其病情进展。

Objective To study the cardiovascular complications and its Chinese medical syndromes of chronic renal failure （CRF）, Methods The primary diseases and Chinese medical syndromes were surveyed,and statistically analyzed by SPSS software. Results The total incidence was 41.51% in non-dialysis CRF patients,26.62%,6.92% and 5.45% in glomerulonephritis CRF, hypertensive CRF and diabetic CRF respectively;with the worsening of renal function,cardiovascular complications increased, with direct pmportion;hypertensive CRF and diabetic CRF were vulnerable to induce cardiovascular diseases,respectively by 64.71% and 60.47%. These cardiovascular diseases were of spleen-kidney yang-deficiency by 87.50%,with dampness and blood-stasis in 92.93%. Conclusion The cardiovascular diseases are based upon CRF.