期刊文献+

丙硫咪唑15或30mg/(kg·d)治疗蛛网膜下腔和脑室内囊虫病的试验

Albendazole trial at 15 or 30 mg/kg/day for subarachnoid and intraventricular cysticercosis
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摘要 Thirty-six patients with subarachnoid and intraventricular cysticercosis were randomly assigned to receive albendazole at 15 or 30 mg/kg/day plus dexamethasone for 8 days. Results favored a higher dose, with larger cyst reduction on MRI at 90 and 180 days and higher albendazole sulfoxide levels in plasma. An albendazole course at 30 mg/kg/day combined with corticosteroids is safe and more effective than the usual dose. A single treatment was insufficient in intraventricular and giant cysts. Thirty-six patients with subarachnoid and intraventricular cysticercosis were randomly assigned to receive albendazole at 15 or 30 mg/kg/day plus dexamethasone for 8 days. Results favored a higher dose, with larger cyst reduction on MRI at 90 and 180 days and higher albendazole sulfoxide levels in plasma. An albendazole course at 30 mg/kg/day combined with corticosteroids is safe and more effective than the usual dose. A single treatment was insufficient in intraventricular and giant cysts.
出处 《世界核心医学期刊文摘(神经病学分册)》 2006年第9期9-9,共1页 Digest of the World Core Medical Journals:Clinical Neurology
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