真菌性角膜溃疡30例临床分析

Clinical research of 30 cases fungal corneal ulcer

目的探讨角膜在感染真菌后的临床表现及治疗转归的特点。方法确诊真菌性角膜溃疡,按抗真菌进行规范药物治疗,每天观察病变角膜的改变,探索有利于缩短真菌性角膜溃疡病程的有关措施。如刮除分泌物、物理盐水冲洗、点血清等。结果真菌性角膜溃疡常伴有前房炎症反应,用药治疗有效时自觉症状好转,病情开始转向稳定,分泌物减少,溃疡面趋平,有少量新生血管长入,愈合后留有薄翳、班翳或白斑,对视力有不同程度影响。结论真菌性角膜溃疡的治疗有赖于诊断明确,及时治疗,规范用药。树立患者战胜疾病的信心,取得配合,不能随意间断、停药、临床上在未明确角膜炎症性质前应注意慎用激素和抗生素。点血清有利于提高局部抵抗力,减少炎症反应,促进溃疡愈合。

Purpose To investigate the clinical characteristics of fungal corneal ulcer and it＇ s prognosis after treatment. Methods Thirty cases of fungal corneal ulcer were treated with anti-fungal drugs and methods,such as scraping the degenerated tissue,administered with autologous sernm.Results：Fungal corneal ulcer after accompanied with inflammation in anterior chamber.After effective medication,the ulcers healed and corneas became slightly neovascularied,clouds or scars were left in corneas and visual acurty became worse in various degrees.Conclusions：Treament of fungal corneal ulcer depended on right diagnosis and proper medicaion in time.