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28例职业性尘肺伴发肺癌的超微病理研究 被引量:1

A STUDY OF ELECTRON MICROSCOPY AMONG 28 PNEUMOCONIOSIS ASSOCIATED WITH LUNG CANCER
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摘要 本文报告了28例尘肺伴发肺癌的病理及超微结构改变,一般特点是:发病年龄偏早(64%在41~49岁确诊为肺癌)、有中度以上吸烟史、预后差。病理特点是:全部病例除尘性病变外均有支气管树上皮的慢性损害(变性和增生)、肺内纤维化病变周围的肺泡上皮增生。28例肺癌的光-电镜诊断符合率为39.3%,不符合的占60.7%。电镜诊断结果为:单纯鳞癌4例、单纯腺癌3例、单纯Apud肿瘤1例、单纯间皮瘤2例、鳞腺(或腺鳞)混合癌10例、鳞癌和Apud肿瘤混合3例、腺癌和Apud肿瘤混合2例、鳞腺和Apud混合3例。上述全部肿瘤均来源于支气管表面上皮(基底细胞、粘液颗粒细胞和Apud细胞)和间皮细胞,电镜诊断反映了瘤细胞不同方向分化和不同配比的组合。 Electron microscopic pathologic investigation of 28 cases of pneumoconiosis with lung cancer was reported.General characters:lung cancer was diagnosed at younger ages than in general population (64% lung cancer diagnosed at 41-49 yrs old);27 Patients are smokers; bad prognosis. Pathologic characters: in addition to pneumoconiotic lesions,most of cases have multiple foci of bronchial epithelium degeneration and proliferation or proliferation of alveolar epithelium. Based on electron microscopic diagnosis 28 lung cancers were: simple squamous cancer 4 cases; simple adenocarcinoma 3 cases; simple Apudoma 1 case; simple mesothelioma 2 cases;squamous and adeno mixed cancer 10 cases; squamous and Apud mixed tumors 3 cases; adenocarcinoma and Apud mixed tumors 2 cases; squamous and adenocarcinoma and Apud mixed tumors 3 cases.
出处 《劳动医学》 1996年第4期193-196,共4页
关键词 尘肺 职业病 肺肿瘤 超微结构 病理 Pathology, Electron microscopy, Pneumoconiosis, Lung cancer
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  • 1王炳森,王明贵,程德成,梁淑容,郑志仁,罗朝宗.石棉肺并发肺内恶性肿瘤的病理研究[J]中华劳动卫生职业病杂志,1987(03).

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