摘要
[目的]研究羟丙基甲基纤维素对磷酸钙骨水泥可注射性的影响。[方法]用注射能力系数法和稠度测定法对含不同浓度HPMC(0~4%)的CPC的注射性能进行评价。[结果]增加HPMC的浓度,CPC的注射性能也增加。HPMC在2%时,注射性能最好,注射能力系数达95%,稠度最低,对水泥的固化时间无明显影响。HPMC超过3%后注射性能开始下降,至4%时注射能力系数降至90%。[结论]适当浓度的HPMC可以很好的改善CPC的流变学性能,增加其可注射性能,适于微创骨科的应用。
[ Objective] To study the influence of hydroxypropyl methyl cellulose (HPMC) on injectability of calcium phosphate cements (CPC). [ Method ] Calcium phosphate cement (ICPC) with different content of HPMC (0 -4% ) was prepared. Injectability coefficient and consistency were tested to evaluate the injectability of the cements. [ Result] Injectability increased as HPMC content increased. CPC injectability coefficient reached to 95% with lowest consistency when HPMC increased to 2%. CPC with 2% HPMC could be injected from syringe completely. Injectability began decrease when HPMC beyond 3%. Injectability decreased to 90% as HPMC increased to 4% ,2% HPMC increased the injectability and decreased the consistency significantly, without any influence of setting time. [ Conclusion] Rheology and injectability of CPC can be improved by HPMC significantly,Injection of CPC with 2% HPMC can be used for mini -invasive orthopedic surgery.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2006年第18期1407-1409,共3页
Orthopedic Journal of China
基金
本课题由国家自然科学基金资助(30500516)
关键词
磷酸钙
骨水泥
可注射性
羟丙基甲基纤维素
影响
calcium phosphate
bone cement
injectability
hydroxypropyl methyl cellulose(HPMC)
effect