生活事件、A型性格与青少年白发发病关系的病例对照研究

A case control study on relationship between life events and type A behavior and juvenile poliosis

目的研究生活事件和Ａ型性格与青少年白发发病的关系。方法以有白发２０根以上为标准选择１０１名青少年病例，按１∶１比例选择相应对照，用“正常中国人生活事件量表”和“Ａ型性格问卷”进行询问调查。结果生活事件变化单位数即Ｌｃｕ≥１５０者发生青少年白发的危险比Ｌｃｕ＜１５０者高３．５６倍（ＯＲ＝３．５６，χ２＝１２．９Ｐ＜０．０１）；Ａ型性格者发生青少年白发的危险比非Ａ型性格者高２．３倍（ＯＲ＝２．３１，χ２＝６．７２Ｐ＜０．０１）；在有遗传史的对子中，Ｌｃｕ≥１５０者和Ａ型性格者发生青少年白发的危险分别是Ｌｃｕ＜１５０者和非Ａ型性格者的１１倍（ＯＲ＝１１，χ２＝１５．０４Ｐ＜０．０１）和３．２倍（ＯＲ＝３．２，χ２＝４．７６Ｐ＜０．０５）；在Ｌｃｕ＜１５０的对子中，Ａ型性格者发生青少年白发的危险是非Ａ型性格者的２．８３倍（ＯＲ＝２．８３，χ２＝４．３５Ｐ＜０．０５）。结论生活事件和Ａ型性格是青少年白发的重要病因，值得深入研究。

Objective To study the relationship between life events and Type A behavior and juvenile poliosis.Methods 101 juveniles each having more than 20 grey hairs were selected and another 101 juveniles served as controls. The investigation was conducted on the basis of 'Standard Chinese Life Condition Tabulation' and 'Type A Behavior Questionaire' Results The risk of grey hair among people with Lcu≥150(Life Condition Unit) is 3.56 times higher than among those with Lcu<150(OR=3.56,χ 2=12.9,P<0.01);Those with type A behavior have a higher risk of poliosis than those with non type A behavior(OR=2.31,χ 2=6.72,P<0.01);Among the pairs with hereditary history,the risks of poliosis for those with Lcu≥150 and type A behavior are much higher than that for those with Lcu<150 and non type A behavior,they are 11 times(OR=11,χ 2=15.04,P<0.01)and 3.2 times(OR=3.2,χ 2=4.76,P<0.05)respectively.While among the pairs Lcu<150,the risk of poliosis in the students having type A behavior is 2.83 times(OR=2.83,χ 2=4.35,P<0.05)higher than that in those having non type A behavior.Conclusions Life events and type A behavior are the important cause of juvenile poliosis.