原发性乳腺淋巴瘤的诊断和治疗

Diagnosis and treatment of primery breast lymphoma

目的:探讨原发性乳腺淋巴瘤(PBL)的临床特点、病理性质及诊断和治疗情况。方法:分析1998年至2005年经病理证实的5例PBL患者诊治情况。结果:5例PBL患者中,1例确诊后1个月内死亡;2例行乳腺癌改良根治术后行6个疗程化疗,现已分别生存4年和3年,其中1例手术2年后发现腹股沟淋巴结转移;2例肿块局部切除已3个月,目前正在化疗中。结论:PBL的诊断主要依据肿瘤切除标本常规病理和免疫组化检查,一般采取化疗为主的综合治疗。

Objective：To explore the clinic and pathologic characteristics of primary breast lymphoma （PBL） for its diagnosis and treatment. Methods： Five cases of PBL that has been diagnosed during 1998 -2005 were analyzed. Results： One patient died 1 month after her final diagnosis. Tow patients have survived 4 and 3 years, respectively, after radical operation plus chemotherapy, although inguinal lymphatic metastasis was found in the later one 2 years after her operation. Another two patients have been accepting chemotherapy for 3 months after their local resection. Conclusion： PBL is diagnosed basically by methods of pathology and immunohistochemistry, and treated mainly by chemotherapy combining with other therapies.